Fatal multiorgan failure due to yellow fever vaccine-associated viscerotropic disease

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Fatal Yellow Fever Vaccine–Associated Viscerotropic Disease — Oregon, September 2014

In September 2014, a previously healthy Oregon woman in her 60s went to a hospital emergency department with malaise, dyspnea, vomiting, and diarrhea of 3-5 days' duration. She reported no recent travel, ill contacts, or dietary changes. Six days earlier, she had received a single dose of yellow fever vaccine and typhoid vaccine before planned travel to South America.

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Rare case of fatal yellow fever vaccine-associated viscerotropic disease.

This report describes a case of yellow fever vaccine-associated viscerotropic disease (YEL-AVD) that occurred after vaccination in a 22-year-old female. Our patient presented with a clinical syndrome of fever, headache, nausea, and vomiting, which quickly progressed to multiorgan failure and ultimately death on hospital day 4. YEL-AVD is an extremely rare condition reported only a few times in ...

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Yellow fever vaccine-associated viscerotropic disease: current perspectives

PURPOSE To assess those published cases of yellow fever (YF) vaccine-associated viscerotropic disease that meet the Brighton Collaboration criteria and to assess the safety of YF vaccine with respect to viscerotropic disease. LITERATURE SEARCH Ten electronic databases were searched with no restriction of date or language and reference lists of retrieved articles. METHODS All abstracts and t...

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Defining risk groups to yellow fever vaccine-associated viscerotropic disease in the absence of denominator data.

Several risk groups are known for the rare but serious, frequently fatal, viscerotropic reactions following live yellow fever virus vaccine (YEL-AVD). Establishing additional risk groups is hampered by ignorance of the numbers of vaccinees in factor-specific risk groups thus preventing their use as denominators in odds ratios (ORs). Here, we use an equation to calculate ORs using the prevalence...

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Risk of yellow fever vaccine-associated viscerotropic disease among the elderly: a systematic review.

Yellow fever vaccine-associated viscerotropic disease (YEL-AVD) is a rare and serious adverse event of the yellow fever (YF) vaccine that mimics wild-type YF. Research shows there may be an increased risk of YEL-AVD among the elderly population (≥ 60-65 years old), however this research has yet to be accumulated and reviewed in order to make policy recommendations to countries currently adminis...

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ژورنال

عنوان ژورنال: Vaccine

سال: 2007

ISSN: 0264-410X

DOI: 10.1016/j.vaccine.2007.08.061